Luteolin, an Abundant Dietary Component is a Potent Anti-leishmanial Agent that Acts by Inducing Topoisomerase II-mediated Kinetoplast DNA Cleavage Leading to Apoptosis
Molecular Medicine2000Vol. 6(6), pp. 527–541
Citations Over TimeTop 10% of 2000 papers
Bidyottam Mittra, Asim Saha, Arnab Roy Chowdhury, Chiranjib Pal, Suparna Mandal, Sibabrata Mukhopadhyay, Santu Bandyopadhyay, Hemanta K. Majumder
Abstract
Luteolin and quercetin are effective antileishmanial agents. Quercetin has nonspecific effects on normal human T cells, but luteolin appears nontoxic. So, luteolin can be a strong candidate for antileishmanial drug design.
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