Increased Salt-Sensitivity in Endothelial Nitric Oxide Synthase–Knockout Mice
American Journal of Hypertension2006Vol. 19(12), pp. 1264–1269
Citations Over TimeTop 10% of 2006 papers
Abstract
The eNOS-/- mice exhibit an increased blood pressure response to a high-salt diet. This finding suggests that eNOS normally provides an important contribution to the body's adaptation to a salt load and that reduced production of NO by eNOS may promote salt-sensitivity and salt-induced hypertension.
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