Architecture and Characteristics of Bacterial Nanotubes
Citations Over TimeTop 10% of 2016 papers
Abstract
Bacteria display an array of contact-dependent interaction systems that have evolved to facilitate direct cell-to-cell communication. We have previously identified a mode of bacterial communication mediated by nanotubes bridging neighboring cells. Here, we elucidate nanotube architecture, dynamics, and molecular components. Utilizing Bacillus subtilis as a model organism, we found that at low cell density, nanotubes exhibit remarkable complexity, existing as both intercellular tubes and extending tubes, with the latter frequently surrounding the cells in a “root-like” fashion. Observing nanotube formation in real time showed that these structures are formed in the course of minutes, displaying rapid movements. Utilizing a combination of super-resolution, light, and electron microscopy, we revealed that nanotubes are composed of chains of membranous segments harboring a continuous lumen. Furthermore, we discovered that a conserved calcineurin-like protein, YmdB, presents in nanotubes and is required for both nanotube production and intercellular molecular trade.
Related Papers
- → ВПЛИВ BACILLUS SUBTILIS НА ПОРОСЯТ НА ВІДЛУЧЕННІ(2022)4 cited
- → СВОЙСТВА ШТАММОВ BACILLUS SUBTILIS КАК ПРОДУЦЕНТОВ АМИЛАЗ ПРИ ПРОИЗВОДСТВЕ САХАРОСОДЕРЖАЩЕЙ КОРМОВОЙ ДОБАВКИ(2020)1 cited
- 산란계에 Bacillus subtilis의 급여가 계란 품질, 혈액 성상 및 분내 암모니아태 질소 함량에 미치는 영향(2005)
- → 生物殺菌劑Bacillus subtilis WG6-14作為產蛋雞益生菌及其排遺於植物病害防治應用之評估(2008)
- 한외여과 막에 의한 대장균과 Bacillus Subtilis균의 제거(2015)