Survival of patients with oropharyngeal squamous cell carcinomas (OPSCC) in relation to TNM 8 – Risk of incorrect downstaging of HPV-mediated non-tonsillar, non-base of tongue carcinomas
European Journal of Cancer2020Vol. 139, pp. 192–200
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Linda Marklund, Stefan Holzhauser, Caroline de Flon, Mark Zupancic, David Landin, Aeneas Kolev, Linnea Haeggblom, Eva Munck‐Wikland, Lalle Hammarstedt‐Nordenvall, Tina Dalianis, Anders Näsman
Abstract
Our results indicate a risk of misclassification of patients with otherOPSCC and low TNM-8 stage. We suggest that p16 should only be evaluated in TSCC/BOTSCC and that patients with otherOPSCC should all be staged as patients with HPV-unrelated (p16-) OPSCC.
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