TLR-2 and TLR-4 expression in monocytes of newborns with late-onset sepsis
Jornal de Pediatria2014Vol. 90(5), pp. 472–478
Citations Over TimeTop 12% of 2014 papers
Ana Carolina Costa Redondo, Maria Esther Jurfest Rivero Ceccon, Ana Lúcia Silveira-Lessa, Camila Quinello, Patrícia Palmeira, Werther Brunow de Carvalho, Magda Carneiro‐Sampaio
Abstract
This study investigated the innate immune response in septic newborns. Septic newborns that relied almost exclusively on the innate immune system showed little in vivo response at monocyte activation, suggesting impaired immune response and increased susceptibility to infection.
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