A Review of Clinical Trials With an Adaptive Design and Health Economic Analysis
Value in Health2019Vol. 22(4), pp. 391–398
Citations Over TimeTop 10% of 2019 papers
Laura Flight, Fahid Arshad, Rachel Barnsley, Kian Patel, Steven A. Julious, Alan Brennan, Susan Todd
Abstract
Appropriate consideration is rarely given to the health economic analysis of adaptive designs. Opportunities to use health economic outcomes in the design and analysis of adaptive trials are being missed. Further work is needed to establish whether adaptive designs and health economic analyses can be used together to increase the efficiency of health technology assessments without compromising accuracy.
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