Validation of inter-eye difference thresholds in optical coherence tomography for identification of optic neuritis in multiple sclerosis
Multiple Sclerosis and Related Disorders2020Vol. 45, pp. 102403–102403
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Gabriel Bsteh, Harald Hegen, Patrick Altmann, Michael Auer, Klaus Berek, Anne Zinganell, Franziska Di Pauli, Paulus Rommer, Florian Deisenhammer, Fritz Leutmezer, Thomas Berger
Abstract
Inter-eye differences of ≥4 μm for GCIPL and to a lesser degree ≥5 μm for RNFL are robust thresholds for identifying unilateral optic nerve lesions. These thresholds could be used to demonstrate previous symptomatic and possibly asymptomatic ON and might be included into a new version of the diagnostic criteria.
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