Doxycycline as an antimalarial: Impact on travellers’ diarrhoea and doxycycline resistance among various stool bacteria – Prospective study and literature review
Travel Medicine and Infectious Disease2022Vol. 49, pp. 102403–102403
Citations Over TimeTop 16% of 2022 papers
Abstract
Our prospective data and the literature review together suggest the following: 1) doxycycline does not prevent TD; 2) doxycycline use favours acquisition of doxy/tetracycline-co-resistant intestinal bacteria; 3) although doxycycline does not predispose to travel-related ESBL-PE acquisition per se, it selects ESBL-PE strains co-resistant to doxycycline; 4) doxycycline resistance rates are high among stool bacteria in general with no evidence of any tendency to decrease.
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