Analysis of Octyl- and Nonylphenol and Their Ethoxylates in Water and Sediments by Liquid Chromatography/Tandem Mass Spectrometry

Citations Over TimeTop 10% of 2003 papers

Abstract

The ubiquitous presence of alkylphenol ethoxylates in the environment as well as concern for endocrine disruption effects in biota caused by their degradation products (such as octyl- and nonylphenol) has raised interest in the environmental fate of these compounds. As part of an effort to model their behavior in a subestuary of the Chesapeake Bay, a quantitative method for the analysis of octyl- and nonylphenol, and their ethoxylates (1-5) in water and sediment was developed. Extraction procedures are based on solid-phase extraction techniques. Identification and quantitation of the analytes is done by liquid chromatography coupled to tandem mass spectrometry. Instrument detection limits for the compounds ranged from 0.1 to 9 pg injected on column, which allowed method detection limits of 0.04-3 ng/L in water and 0.2-13 ng/g of dry weight in sediment. The method was used to analyze water and sediment from the Back River, MD, where concentrations for the individual compounds ranged from <8 to 200 ng/L in water and <9 to 6700 ng/g of dry weight in sediment. Additionally, structural information obtained in the mass spectrometer is presented that supports previous observations that nonylphenol and its ethoxylates are composed mainly of isomers with a tertiary alpha-carbon.

Related Papers

• → Multiple stage mass spectrometry: the next generation tandem mass spectrometry experiment(1994)14 cited
• → Identification of phase I metabolites of cardiovascular and anti-ulcer drugs in surface water samples with liquid-chromatography–mass spectrometry methods(2011)7 cited
• → Fast atom bombardment mass spectrometry and tandem mass spectrometry in antibiotics: Identification of nucleoside antitumor antibiotic toyocamycin in fermentation broth(1984)9 cited
• Aerobic biodegradation pathways of nonylphenol ethoxylates elucidated by liquid chromatography - electrospray tandem mass spectrometry.(2000)
• → Test Method for Determination of Nonylphenol, p-tert-Octylphenol, Nonylphenol Monoethoxylate and Nonylphenol Diethoxylate in Environmental Waters by Liquid Chromatography/Tandem Mass Spectrometry(2023)