Hyaluronic Acid-Coated Silver Nanoparticles As a Nanoplatform for in Vivo Imaging Applications
ACS Applied Materials & Interfaces2016Vol. 8(39), pp. 25650–25653
Citations Over TimeTop 18% of 2016 papers
Xin Zhang, Meinan Yao, Muhua Chen, Liqiang Li, Chengyan Dong, Yi Hou, Huiyun Zhao, Bing Jia, Fan Wang
Abstract
An efficient chemical reduction protocol has been developed for the synthesis of hyaluronic acid-coated silver nanoparticles (HA-Ag NPs) that are spherical, ultrasmall and monodisperse. The as-synthesized HA-Ag NPs not only exhibited excellent long-term stability and low cytotoxicity but also could be used as a nanoplatform for X-ray computed tomography (CT) and single-photon emission computed tomography (SPECT) imaging after being radiolabeled with 99mTc.
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