Dual Oxidation State Tandem Catalysis in the Palladium-Catalyzed Isomerization of Alkynyl Epoxides to Furans
ACS Catalysis2018Vol. 8(9), pp. 8290–8295
Citations Over TimeTop 13% of 2018 papers
Abstract
A two-catalyst system consisting of different oxidation states of palladium is described, which mediates the isomerization of alkynyl epoxides to furans. In a process termed "dual oxidation state tandem catalysis", a multistep isomerization pathway is delineated in which the different metal oxidation states and ligands play independent mechanistic roles, but which, in combination, enable the use of milder reaction conditions and lower catalyst loadings than a single catalyst in isolation. In the present context, this rare example of a homobimetallic catalytic transformation provides a mild, scalable, and atom-efficient route for furan synthesis.
Related Papers
- → Mechanistic Insights into the Post‐Cyclization Isomerization in Gold‐Catalyzed 7‐exo‐dig‐Hydroarylations(2015)38 cited
- → Isomerization reactions of n-hexane on partially reduced MoO3/TiO2(2007)33 cited
- → Anisatinic acid and isoanisatinic acid, isomerization products of anisatin(1968)10 cited
- → Novel insight into the photochemical cis-trans isomerization of olefins.(1986)10 cited
- → Isomerization(2017)