A FRET-based Ratiometric Fluorescent Probe for Nitroxyl Detection in Living Cells
ACS Applied Materials & Interfaces2015Vol. 7(9), pp. 5438–5443
Citations Over TimeTop 10% of 2015 papers
Abstract
HNO has recently been found to possess distinct biological functions from NO. Studying the biological functions of HNO calls for the development of sensitive and selective fluorescent probes. Herein, we designed and synthesized a FRET-based ratiometric probe to detect HNO in living cells. Our studies revealed that the probe is capable of detecting HNO in a rapid and ratiometric manner under physiological conditions. In bioimaging studies, the probe displayed a clear color change from blue to green when treated with HNO.
Related Papers
- → Development of Probes for Cellular Functions Using Fluorescent Proteins and Fluorescence Resonance Energy Transfer(2011)235 cited
- → Plasmon‐Enhanced Fluorescence Resonance Energy Transfer(2019)68 cited
- → Dual-Switching FRET (dsFRET) Imaging Based on Photoswitchable Donor-Acceptor Pair(2015)1 cited
- Structural analysis of nucleic acids by using fluorescence resonance energy transfer (FRET).(1997)
- → Outlook on FRET: The Future of Resonance Energy Transfer(2013)3 cited