Exploration of Fundamental and Synthetic Aspects of the Intramolecular 4 + 3 Cycloaddition Reaction
Accounts of Chemical Research2001Vol. 34(7), pp. 595–605
Citations Over TimeTop 10% of 2001 papers
Abstract
In this Account, a summary of our work in the exploration and development of intramolecular 4 + 3 cycloaddition reactions between dienes and allylic cations is presented. Alkoxyallylic sulfones are useful precursors for the generation of allylic cations which are good dienophiles. Such substrates allowed a number of important pieces of data concerning the cycloaddition to be obtained. The evolution of the work has involved pursuing other methods for allylic cation generation, an investigation of stereochemical variables and applications, including the total syntheses of aphanamol I, widdrol, and (+)-dactylol.
Related Papers
- → Transition metal-catalyzed allylic substitution reactions with unactivated allylic substrates(2015)668 cited
- → A silver(I)-catalyzed intramolecular Ficini’s [2+2] cycloaddition employing ynamides(2015)20 cited
- → One-Pot Synthesis of Homoallylic Alcohols via a Facile Conversion of Allylic Alcohols into Allylic Iodides(1989)30 cited
- → ChemInform Abstract: Allylic Selenides in Organic Synthesis: New Methods for the Synthesis of Allylic Amines.(1987)
- → Addition Reactions: Cycloaddition(2014)