A Whole More Than the Sum of Its Synthetic Parts
ACS Chemical Biology2008Vol. 3(1), pp. 27–29
Abstract
Synthetic biology is the realization of systems with desired behavior using biological materials. A recent addition to the field is a bipartite consortium of the bacterium Escherichia coli in which each species harbors complementary gene circuits that actuate only when both are present above a critical density. This bacterial "consensus" system, functional in liquid, solid, and biofilm niches, represents a novel strategy that raises the bar in terms of the specificity and complexity of tasks performed by engineered organisms.
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