Type 2 Diabetes Mellitus: Limitations of Conventional Therapies and Intervention with Nucleic Acid-Based Therapeutics

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Abstract

ADVERTISEMENT RETURN TO ISSUEPREVReviewNEXTType 2 Diabetes Mellitus: Limitations of Conventional Therapies and Intervention with Nucleic Acid-Based TherapeuticsGanesh R. Kokil†, Rakesh N. Veedu*‡§∥, Grant A. Ramm⊥#, Johannes B. Prins∇, and Harendra S. Parekh*†View Author Information† School of Pharmacy, Pharmacy Australia Centre of Excellence, The University of Queensland, Brisbane, QLD 4102, Australia§ Center for Comparative Genomics, Murdoch University, 90 South Street, Murdoch, WA 6150, Australia∥ Western Australian Neuroscience Research Institute, Perth, WA 6150, Australia‡ School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane QLD 4072 Australia⊥ The Hepatic Fibrosis Group, QIMR Berghofer Medical Research Institute, Brisbane, QLD 4006, Australia# Faculty of Medicine and Biomedical Sciences, The University of Queensland, Brisbane, QLD 4006, Australia∇ Mater Research Institute, The University of Queensland, Brisbane, QLD 4101, Australia*R.N.V. e-mail: [email protected] or [email protected]*H.S.P. e-mail: [email protected]Cite this: Chem. Rev. 2015, 115, 11, 4719–4743Publication Date (Web):April 28, 2015Publication History Received29 May 2014Published online28 April 2015Published inissue 10 June 2015https://pubs.acs.org/doi/10.1021/cr5002832https://doi.org/10.1021/cr5002832review-articleACS PublicationsCopyright © 2015 American Chemical SocietyRequest reuse permissionsArticle Views4171Altmetric-Citations63LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Anatomy,Carbohydrates,Genetics,Peptides and proteins,Therapeutics Get e-Alerts

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