Recognition and Reaction of Metallointercalators with DNA
Chemical Reviews1999Vol. 99(9), pp. 2777–2796
Citations Over TimeTop 1% of 1999 papers
Abstract
The design of small complexes that bind and react at specific sequences of DNA becomes important as we begin to delineate, on a molecular level, how genetic information is expressed. A more complete understanding of how to target DNA sites with specificity will lead not only to novel chemotherapeutics but also to a greatly expanded ability for chemists to probe DNA and to develop highly sensitive diagnostic agents.
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