Mononuclear CuII−Phenolate Bioinspired Complex is Catalytically Promiscuous: Phosphodiester and Peptide Amide Bond Cleavage
Inorganic Chemistry2009Vol. 48(7), pp. 2711–2713
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Maurício César Bof de Oliveira, Deise J. Mazera, Marciela Scarpellini, Patrícia Severino, Ademir Neves, Hernán Terenzi
Abstract
In this work, the cleavage activity of the metal complex [Cu(C(21)H(21)N(3)O(2))(OH(2))(2)](2+) is demonstrated to occur toward double-stranded DNA, in addition to its previously described amide bond cleavage activity, thus suggesting catalytic promiscuity for this complex.
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