Kinetics of Disassembly of a DNA-Bound Porphyrin Supramolecular Array
Citations Over TimeTop 20% of 2002 papers
Abstract
trans-Bis(N-methylpyridinium-4-yl)diphenylporphine forms extended, organized assemblies on DNA templates under appropriate conditions of concentration, ionic strength, and temperature. Addition of beta-cyclodextrin to these arrays leads to their disassembly as evidenced by changes in extinction, circular dichroism, and resonance light scattering spectra. The structure or flexibility of the polymer template has an effect on the rate of disassembly; the reaction is faster on a poly(dG-dC)(2) surface than on ct DNA. The kinetic profiles for the disassembly process can be fit with great precision with a two-kinetic parameter equation in which the rate constant is itself a function of time. The reaction rate, studied in the presence of excess beta-CD, shows a dependence on the mode of detection. A model is presented to account for these observations in which the arrays become increasingly reactive with time due to beta-CD attack at the interior of the porphyrin assemblies as well as the ends.
Related Papers
- → Molecular design of supramolecular polymers with chelated units and their application as functional materials(2018)24 cited
- → The Contributions of Supramolecular Kinetics to Dynamics of Supramolecular Polymers(2022)6 cited
- → Hydrogen bonding induced order in supramolecular polymers(2011)1 cited
- → Supramolecular Polymers based on Pillararenes(2015)
- Self-healing Behavior of Supramolecular Polymers(2014)