First Artificial Receptors and Chemosensors toward Phosphorylated Peptide in Aqueous Solution
Journal of the American Chemical Society2002Vol. 124(22), pp. 6256–6258
Citations Over TimeTop 1% of 2002 papers
Abstract
The first fluorescent chemosensors toward a native phosphorylated peptide are successfully synthesized. Dinuclear zinc(II)-dipicolylamine-based anthracene (1, 2) can selectively recognize and sense phosphorylated species with an increase in the fluorescence intensity. We also demonstrated that these artificial receptors fluorometrically detect a phosphorylated peptide with high affinity (>107 M-1) in aqueous solution.
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