Thermally Reversible Formation of Microspheres through Non-Covalent Polymer Cross-Linking
Journal of the American Chemical Society2003Vol. 125(37), pp. 11249–11252
Citations Over TimeTop 10% of 2003 papers
Abstract
Bis-thymine units were used to noncovalently cross-link a complementary diamidopyridine-functionalized copolymer. Upon combination in noncompetitive solvents, discrete micron-scale spherical aggregates were formed arising from specific three-point polymer-cross-linker hydrogen bonding interactions. The diameter of these microspheres could be controlled through spacer structure. The cross-linking process was fully thermally reversible, with complete dissolution observed at 50 degrees C and reformation of the aggregates upon return to ambient temperature. This process could be repeated multiply, with lower particle dispersity observed arising from the annealing process.
Related Papers
- → Polymeric Microspheres for Medical Applications(2010)208 cited
- → Effect of phlorotannins modification on the physicochemical, structural and functional properties of soybean protein isolate and controlled hydrolysates: Covalent and non-covalent interactions(2023)56 cited
- → ▪ FEATURED ABSTRACTDosimetric analysis of 90Y glass and resin microsphere distributions in hepatic tumors: from the microsphere coverage to the absorbed dose(2016)
- Research Progress on microspheres preparation of Chinese medicine(2013)
- [Proof of the formation of covalent bonds during staining of histologic preparations with procion dyes].(1976)