Raman Dye-Labeled Nanoparticle Probes for Proteins
Journal of the American Chemical Society2003Vol. 125(48), pp. 14676–14677
Citations Over TimeTop 10% of 2003 papers
Abstract
In this paper, we demonstrate how one can chemically design Raman dye-functionalized nanoparticle probes with specific protein-binding affinities and use these probes, coupled with surface-enhanced Raman scattering (SERS) spectroscopy, to perform multiplexed screening of protein-small molecule interactions and protein-protein interactions in a protein microarray format.
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