Enantioselective Michael Reaction of Malonates to Nitroolefins Catalyzed by Bifunctional Organocatalysts
Journal of the American Chemical Society2003Vol. 125(42), pp. 12672–12673
Citations Over TimeTop 1% of 2003 papers
Abstract
Michael reaction of malonates to nitroolefins with chiral bifunctional organocatalysts, bearing both a thiourea and tertiary amino group, afforded Michael adducts with high yields and enantioselectivities (up to 95%, up to 93% ee).
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