Nanoscale Size Effect of Magnetic Nanocrystals and Their Utilization for Cancer Diagnosis via Magnetic Resonance Imaging
Journal of the American Chemical Society2005Vol. 127(16), pp. 5732–5733
Citations Over TimeTop 1% of 2005 papers
Young‐wook Jun, Yong‐Min Huh, Jin‐sil Choi, Jae‐Hyun Lee, Ho‐Taek Song, Sung Jun Kim, Sarah Yoon, Kyung‐Sup Kim, Jeon‐Soo Shin, Jin‐Suck Suh, Jinwoo Cheon
Abstract
Since the use of magnetic nanocrystals as probes for biomedical system is attractive, it is important to develop optimal synthetic protocols for high-quality magnetic nanocrystals and to have the systematic understanding of their nanoscale properties. Here we present the development of a synthetically controlled magnetic nanocrystal model system that correlates the nanoscale tunabilities in terms of size, magnetism, and induced nuclear spin relaxation processes. This system further led to the development of high-performance nanocrystal-antibody probe systems for the diagnosis of breast cancer cells via magnetic resonance imaging.
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