Total Synthesis of (±)-Jiadifenin, a Non-peptidyl Neurotrophic Modulator
Journal of the American Chemical Society2004Vol. 126(44), pp. 14358–14359
Citations Over TimeTop 10% of 2004 papers
Abstract
We report the first total synthesis of jiadifenin (1), the establishment of a modality for its biological evaluation, and the discovery of apparently more potent neurotrophic activity in fully synthetic compound 17, an intermediate en route to 1.
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