Total Synthesis of Ecteinascidin 743
Journal of the American Chemical Society2005Vol. 128(1), pp. 87–89
Citations Over TimeTop 10% of 2005 papers
Abstract
A convergent total synthesis of ecteinascidin 743 is realized from five building blocks of almost equal size. It takes 23 steps from l-3-hydroxy-4-methoxy-5-methyl phenylalanol (5) with an overall yield of 3%.
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