Bacterial Spore Detection by [Tb3+(macrocycle)(dipicolinate)] Luminescence
Journal of the American Chemical Society2007Vol. 129(6), pp. 1474–1475
Citations Over TimeTop 10% of 2007 papers
Abstract
Dipicolinic acid (DPA) is a unique constituent of bacterial spores, a dormant form of Bacillus and Clostridium, which can be detected using DPA-triggered Tb3+ luminescence. [Tb(DO2A)]+ improves the sensitivity of bacterial spore detection over Tb3+(aq) owing to the exclusion of coordinated water molecules and represents the first step toward construction of a DPA receptor site with enhanced binding selectivity. The title ternary [Tb(DO2A)(DPA)]- complex was structurally characterized and features two DO2A-DPA interligand hydrogen interactions that stabilize the complex.
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