Speeding Up Three-Dimensional Protein NMR Experiments to a Few Minutes
Journal of the American Chemical Society2006Vol. 128(28), pp. 9042–9043
Citations Over TimeTop 10% of 2006 papers
Abstract
We demonstrate for different protein samples that three-dimensional HNCO and HNCA correlation spectra may be recorded in a few minutes acquisition time using the band-selective excitation short-transient sequences presented here. This opens new perspectives for the NMR structural investigation of unstable protein samples and real-time site-resolved studies of protein kinetics.
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