Synthesis of Benzonorcaradienes by Gold(I)-Catalyzed [4+3] Annulation
Journal of the American Chemical Society2006Vol. 128(45), pp. 14480–14481
Citations Over TimeTop 10% of 2006 papers
Abstract
A formal [4 + 3]-annulation of vinyl arenes and diynyl propargyl esters is described. A mechanism involving cationic phosphinegold(I)-catalyzed tandem cyclopropanation/hydroarylation to produce the benzonorcaradiene products is proposed. In accord with this mechanism, the alkynyl cyclopropane can also be prepared with excellent regio- and diastereocontrol.
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