Polymer-Caged Lipsomes: A pH-Responsive Delivery System with High Stability
Journal of the American Chemical Society2007Vol. 129(49), pp. 15096–15097
Citations Over TimeTop 10% of 2007 papers
Abstract
Polymer-incorporated liposomes were prepared from preformed liposomes and a cholesterol-functionalized poly(acrylic acid) additive via a simple drop-in procedure. These modified liposomes possess surface-active carboxylate groups that can be cross-linked with telechelic 2,2‘-(ethylenedioxy)bis(ethylamine) linkers, resulting in polymer-caged liposomes (PCLs) that are highly stable and have tunable pH-sensitive responses.
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