Cysteine-Activated Hydrogen Sulfide (H 2 S) Donors
Journal of the American Chemical Society2010Vol. 133(1), pp. 15–17
Citations Over TimeTop 10% of 2010 papers
Abstract
H(2)S, the newly discovered gasotransmitter, plays important roles in biological systems. However, the research on H(2)S has been hindered by the lack of controllable H(2)S donors that could mimic the slow and continuous H(2)S generation process in vivo. Herein we report a series of cysteine-activated H(2)S donors. Structural modifications of these molecules can regulate the rates of H(2)S generation. These compounds can be useful tools in H(2)S research.
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