Cupric Superoxo-Mediated Intermolecular C−H Activation Chemistry
Journal of the American Chemical Society2011Vol. 133(6), pp. 1702–1705
Citations Over TimeTop 10% of 2011 papers
Ryan L. Peterson, Richard A. Himes, Hiroaki Kotani, Tomoyoshi Suenobu, Li Tian, Maxime A. Siegler, Edward I. Solomon, Shunichi Fukuzumi, Kenneth D. Karlin
Abstract
The new cupric superoxo complex [LCu(II)(O(2)(•-))](+), which possesses particularly strong O-O and Cu-O bonding, is capable of intermolecular C-H activation of the NADH analogue 1-benzyl-1,4-dihydronicotinamide (BNAH). Kinetic studies indicated a first-order dependence on both the Cu complex and BNAH with a deuterium kinetic isotope effect (KIE) of 12.1, similar to that observed for certain copper monooxygenases.
Related Papers
- → SOME DEUTERIUM KINETIC ISOTOPE EFFECTS: IV. β-DEUTERIUM EFFECTS IN WATER SOLVOLYSIS OF ETHYL, ISOPROPYL, AND tert-BUTYL COMPOUNDS(1960)14 cited
- → Nitrogen and deuterium kinetic isotope effects on the Menshutkin reaction(1996)17 cited
- → Secondary Deuterium Isotope Effects on Reactions Proceeding Through Carbocations(1983)24 cited
- → Calculations of intrinsic isotope effects and the detection of tunneling in enzyme-catalyzed reactions(1990)10 cited
- Kinetic Deuterium Isotope Effects on the Reactions of 2-(4-Methoxyphenyl)Oxirane in Water Solutions(2006)