Determination of Molecular Configuration by Debye Length Modulation

Citations Over TimeTop 10% of 2011 papers

Abstract

Silicon nanowire field effect transistors (FETs) have emerged as ultrasensitive, label-free biodetectors that operate by sensing bound surface charge. However, the ionic strength of the environment (i.e., the Debye length of the solution) dictates the effective magnitude of the surface charge. Here, we show that control of the Debye length determines the spatial extent of sensed bound surface charge on the sensor. We apply this technique to different methods of antibody immobilization, demonstrating different effective distances of induced charge from the sensor surface.

Related Papers

• → Exact Analytical Solutions of the Nonlinear Three-dimensional Debye Screening in Plasmas(2003)15 cited
• → Study of the Nonlinear Three-dimensional Debye Screening in Plasmas(2000)8 cited
• → Nonlinear Two-Dimensional Debye Screening in Plasmas(1994)
• New analytical solutions of nonlinear two-dimensional Debye screening in plasmas(2001)
• Physics of the Debye temperature(2007)