A Sugar-Functionalized Amphiphilic Pillar[5]arene: Synthesis, Self-Assembly in Water, and Application in Bacterial Cell Agglutination

Citations Over TimeTop 1% of 2013 papers

Abstract

A novel sugar-functionalized amphiphilic pillar[5]arene containing galactose groups as the hydrophlic part and alkyl chains as the hydrophobic part was designed and synthesized. It self-assembles in water to produce nanotubes as confirmed by TEM, SEM, and fluorescence microscopy. These nanotubes, showing low toxicity to both cancer and normal cells, can be utilized as excellent cell glues to agglutinate E. coli. The existence of galactoses on these nanotubes provides multivalent ligands that have high affinity for carbohydrate receptors on E. coli.

Related Papers

• → Recent development of pillar[n]arene-based amphiphiles(2020)80 cited
• → A new amphiphilic pillar[5]arene: synthesis and controllable self-assembly in water and application in white-light-emitting systems(2018)47 cited
• → Dual-responsive self-assembly of a bola-type supra-amphiphile constructed from a new pillar[6]arene-based recognition motif in water and its application in controlled release(2016)19 cited
• → Amphiphilic pillar[ n ]arenes(2018)14 cited
• → An alternative route for the synthesis of hydroxylated pillar[5]arene-based amphiphiles(2018)8 cited