Highly Sequence-Dependent Formation of Fluorescent Silver Nanoclusters in Hybridized DNA Duplexes for Single Nucleotide Mutation Identification
Journal of the American Chemical Society2009Vol. 132(3), pp. 932–934
Citations Over TimeTop 1% of 2009 papers
Abstract
Fluorescent silver nanoclusters were successfully synthesized using hybridized DNA duplexes as capping scaffolds. The formation of these emitters was highly sequence-dependent and could specifically identify a single nucleotide mutation, the sickle cell anemia gene mutation. Furthermore, the identification of single-nucleotide differences using this strategy was extended to more general types of single-nucleotide mismatches.
Related Papers
- → Nanoclusters and nanocluster systems. Assembling, interactions and properties(2001)135 cited
- → Modulation of the Double-Helical Cores: A New Strategy for Structural Predictions of Thiolate-Protected Gold Nanoclusters(2020)18 cited
- → Structural Engineering of Heterometallic Nanoclusters(2015)2 cited
- → Photophysical Characterization of Fluorescent Lysozyme Stabilized Gold Nanoclusters and their Applications(2016)1 cited
- → Assembly of metal nanoclusters(2023)