Zinc-Catalyzed Reduction of Amides: Unprecedented Selectivity and Functional Group Tolerance
Journal of the American Chemical Society2010Vol. 132(6), pp. 1770–1771
Citations Over TimeTop 1% of 2010 papers
Abstract
A novel zinc-catalyzed reduction of tertiary amides was developed. This system shows remarkable chemoselectivity and substrate scope tolerating ester, ether, nitro, cyano, azo, and keto substituents.
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