Complementarity of Combinatorial Chemistry and Structure-Based Ligand Design: Application to the Discovery of Novel Inhibitors of Matrix Metalloproteinases
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Abstract
ADVERTISEMENT RETURN TO ISSUEPREVCommunicationNEXTComplementarity of Combinatorial Chemistry and Structure-Based Ligand Design: Application to the Discovery of Novel Inhibitors of Matrix MetalloproteinasesArlene Rockwell, Mark Melden, Robert A. Copeland, Karl Hardman, Carl P. Decicco, and William F. DeGradoView Author Information Chemical and Physical Sciences The DuPont Merck Pharmaceutical Company Experimental Station, Wilmington, Delaware 19880 Cite this: J. Am. Chem. Soc. 1996, 118, 42, 10337–10338Publication Date (Web):October 23, 1996Publication History Received19 March 1996Published online23 October 1996Published inissue 1 January 1996https://pubs.acs.org/doi/10.1021/ja960897thttps://doi.org/10.1021/ja960897trapid-communicationACS PublicationsCopyright © 1996 American Chemical SocietyRequest reuse permissionsArticle Views277Altmetric-Citations82LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Amides,Inhibition,Inhibitors,Peptides and proteins,Phenyls Get e-Alerts
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