Linezolid (ZYVOX), the First Member of a Completely New Class of Antibacterial Agents for Treatment of Serious Gram-Positive Infections

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Abstract

ADVERTISEMENT RETURN TO ISSUEPerspectiveNEXTLinezolid (ZYVOX), the First Member of a Completely New Class of Antibacterial Agents for Treatment of Serious Gram-Positive InfectionsSteven J. Brickner*†, Michael R. Barbachyn‡, Douglas K. Hutchinson§, and Peter R. Manninen#View Author Information Pfizer Global Research and Development, Groton, Connecticut 06340, AstraZeneca Pharmaceuticals LP, Waltham, Massachusetts 02451, Abbott Laboratories, Abbott Park, Illinois 60064, and Eli Lilly and Company, Indianapolis, Indiana 46285* To whom correspondence should be addressed. Phone: 860-441-8558 . Fax: 860-686-0605. E-mail: [email protected]†Pfizer Global Research and Development.‡AstraZeneca Pharmaceuticals LP.§Abbott Laboratories.#Eli Lilly and Company.Cite this: J. Med. Chem. 2008, 51, 7, 1981–1990Publication Date (Web):March 14, 2008Publication History Received16 January 2008Published online14 March 2008Published inissue 1 April 2008https://pubs.acs.org/doi/10.1021/jm800038ghttps://doi.org/10.1021/jm800038greview-articleACS PublicationsCopyright © 2008 American Chemical SocietyRequest reuse permissionsArticle Views3595Altmetric-Citations153LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Antimicrobial agents,Bacteria,Cyclization,Infectious diseases,Rodent models Get e-Alerts

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