Nonsteroidal Selective Androgen Receptor Modulators (SARMs): Dissociating the Anabolic and Androgenic Activities of the Androgen Receptor for Therapeutic Benefit

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Abstract

ADVERTISEMENT RETURN TO ISSUEPerspectiveNEXTNonsteroidal Selective Androgen Receptor Modulators (SARMs): Dissociating the Anabolic and Androgenic Activities of the Androgen Receptor for Therapeutic BenefitMichael L. Mohler§, Casey E. Bohl§, Amanda Jones§, Christopher C. Coss§, Ramesh Narayanan§, Yali He§, Dong Jin Hwang§, James T. Dalton*§, and Duane D. Miller*§‡View Author Information Preclinical Research and Development, GTx, Inc., 3 North Dunlap Street, Memphis, Tennessee 38163, and Department of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Science Center, 847 Monroe Avenue, Memphis, Tennessee 38163* To whom correspondence should be addressed. For J.T.D.: phone, (901) 507-8604; fax, (901) 844-8078; e-mail, [email protected]. For D.D.M.: phone, (901) 448-6026; fax, (901) 448-3446; e-mail, [email protected]§GTx, Inc.‡University of Tennessee Health Science Center.Cite this: J. Med. Chem. 2009, 52, 12, 3597–3617Publication Date (Web):May 11, 2009Publication History Received6 March 2009Published online11 May 2009Published inissue 25 June 2009https://pubs.acs.org/doi/10.1021/jm900280mhttps://doi.org/10.1021/jm900280mreview-articleACS PublicationsCopyright © 2009 American Chemical SocietyRequest reuse permissionsArticle Views5894Altmetric-Citations158LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-Alertsclose SUBJECTS:Agonists,Anatomy,Ligands,Receptors,Rodent models Get e-Alerts

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