Discovery and Preclinical Pharmacology of a Novel, Potent, Nonsteroidal Estrogen Receptor Agonist/Antagonist, CP-336156, a Diaryltetrahydronaphthalene

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Abstract

ADVERTISEMENT RETURN TO ISSUEPREVLetterNEXTDiscovery and Preclinical Pharmacology of a Novel, Potent, Nonsteroidal Estrogen Receptor Agonist/Antagonist, CP-336156, a DiaryltetrahydronaphthaleneRobert L. Rosati, Paul Da Silva Jardine, Kimberly O. Cameron, David D. Thompson, Hua Zhu Ke, Steven M. Toler, Thomas A. Brown, Lydia C. Pan, Charles F. Ebbinghaus, Anthony R. Reinhold, Nancy C. Elliott, Bradley N. Newhouse, Christina M. Tjoa, Paul M. Sweetnam, Mark J. Cole, Mark W. Arriola, Jeffrey W. Gauthier, D. Todd Crawford, David F. Nickerson, Christine M. Pirie, Hong Qi, Hollis A. Simmons, and George T. TkalcevicView Author Information Central Research Division, Pfizer Inc., Groton, Connecticut 06340 Cite this: J. Med. Chem. 1998, 41, 16, 2928–2931Publication Date (Web):July 11, 1998Publication History Received23 January 1998Published online11 July 1998Published inissue 1 July 1998https://pubs.acs.org/doi/10.1021/jm980048bhttps://doi.org/10.1021/jm980048brapid-communicationACS PublicationsCopyright © 1998 American Chemical SocietyRequest reuse permissionsArticle Views1310Altmetric-Citations115LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Anatomy,Bioavailability,Cholesterol,Receptors,Rodent models Get e-Alerts

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