(R)-3,3,3-Trifluoro-2-hydroxy-2-methylpropionamides Are Orally Active Inhibitors of Pyruvate Dehydrogenase Kinase
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ADVERTISEMENT RETURN TO ISSUEPREVLetterNEXT(R)-3,3,3-Trifluoro-2-hydroxy-2-methylpropionamides Are Orally Active Inhibitors of Pyruvate Dehydrogenase KinaseThomas D. Aicher, Robert C. Anderson, Gregory R. Bebernitz, Gary M. Coppola, Charles F. Jewell, Douglas C. Knorr, Charles Liu, Donald M. Sperbeck, Leonard J. Brand, Robert J. Strohschein, Jiaping Gao, Christine C. Vinluan, Suraj S. Shetty, Carol Dragland, Emma L. Kaplan, Dominick DelGrande, Amin Islam, Xilin Liu, Robert J. Lozito, Wieslawa M. Maniara, R. Erik Walter, and William R. MannView Author Information Novartis Institute for Biomedical Research, 556 Morris Avenue, Summit, New Jersey 07901 Cite this: J. Med. Chem. 1999, 42, 15, 2741–2746Publication Date (Web):July 14, 1999Publication History Received25 May 1999Published online14 July 1999Published inissue 1 July 1999https://pubs.acs.org/doi/10.1021/jm9902584https://doi.org/10.1021/jm9902584rapid-communicationACS PublicationsCopyright © 1999 American Chemical SocietyRequest reuse permissionsArticle Views1315Altmetric-Citations39LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Amides,Assays,Inhibitors,Peptides and proteins,Post-translational modification Get e-Alerts
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