Selective Plasma Hydrolysis of Glucocorticoid γ-Lactones and Cyclic Carbonates by the Enzyme Paraoxonase: An Ideal Plasma Inactivation Mechanism
Citations Over TimeTop 11% of 1999 papers
Abstract
ADVERTISEMENT RETURN TO ISSUEPREVLetterNEXTSelective Plasma Hydrolysis of Glucocorticoid γ-Lactones and Cyclic Carbonates by the Enzyme Paraoxonase: An Ideal Plasma Inactivation MechanismKeith Biggadike, Richard M. Angell, Colin M. Burgess, Rosanne M. Farrell, Ashley P. Hancock, Andy J. Harker, Wendy R. Irving, Chris Ioannou, Panayiotis A. Procopiou, Rupert E. Shaw, Yemisi E. Solanke, Onkar M. P. Singh, Michael A. Snowden, Rob J. Stubbs, Sarah Walton, and Helen E. WestonView Author Information Medicinal Chemistry, Enzyme Pharmacology, Biomet Discovery and Protein Science Units, Glaxo Wellcome Research and Development, Medicines Research Centre, Gunnels Wood Road, Stevenage, Hertfordshire, SG1 2NY, U.K. Cite this: J. Med. Chem. 2000, 43, 1, 19–21Publication Date (Web):December 11, 1999Publication History Received25 August 1999Published online11 December 1999Published inissue 1 January 2000https://pubs.acs.org/doi/10.1021/jm990436thttps://doi.org/10.1021/jm990436trapid-communicationACS PublicationsCopyright © 2000 American Chemical SocietyRequest reuse permissionsArticle Views1373Altmetric-Citations160LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InRedditEmail Other access optionsGet e-AlertscloseSupporting Info (1)»Supporting Information Supporting Information SUBJECTS:Genetics,Lactones,Molecular structure,Peptides and proteins,Plasma Get e-Alerts
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