Application of 2-substituted vinamidinium salts to the synthesis of 2,4-disubstituted pyrroles

Citations Over TimeTop 10% of 1990 papers

Abstract

A variety of 2-substituted vinamidinium salts react with a-amino acid esters under basic conditions to produce 2-carbethoxy-4-substituted-pyrroles in good yield. The overall process represents a short and efficient synthesis of highly functionalized pyrroles from a-substituted acetic acid precursors. Such reactions may involve the intermediacy of azomethine ylids or “pentadienyl like” anions. © 1990, American Chemical Society. All rights reserved.

Related Papers

• → Do Altmetrics Work? Twitter and Ten Other Social Web Services(2013)898 cited
• → An Introduction to Altmetrics(2014)115 cited
• From attention to citation: What are altmetrics and how do they work?(2014)
• Susquehanna Chorale Spring Concert "Roots and Wings"(2017)