A Non-cryogenic Method for the Preparation of 2-(Indolyl) Borates, Silanes, and Silanols
The Journal of Organic Chemistry2002Vol. 67(21), pp. 7551–7552
Citations Over TimeTop 10% of 2002 papers
Abstract
2-Indolyl borates are prepared via addition of LDA to a mixture of N-Boc-indole and triisopropyl borate at 0-5 degrees C. Following acidic hydrolysis, the boronic acids are isolated by crystallization in good to excellent yield (73-99%). The method is quite general, tolerating a wide range of functional groups, and also provides access to 2-silyl derivatives (80-91%).
Related Papers
- → Facile synthesis of silyl allenol ethers and β-silyl enones through reductive silylation of benzoylacetylenes(2022)2 cited
- → SPECTRAL AND CHEMICAL PROPERTIES OF β- AND γ-FUNCTIONAL SILANES(1964)22 cited
- → High-yield electrosynthesis of furylchlorosilanes, silyl and silanylene furans(1998)5 cited
- → Manganese-catalyzed Dehydrogenative Silylation of Alkenes(2022)