A Facile Synthesis of C2,N3-Disubstituted-4-quinazolone
The Journal of Organic Chemistry2004Vol. 69(19), pp. 6474–6477
Citations Over TimeTop 16% of 2004 papers
Abstract
A simple and efficient methodology for the synthesis of C(2),N(3)-disubstituted-4 quinazolones from anilines and N-acylanthranilic acids was developed. The new cyclization conditions are much milder than any other reported protocols and resulted in excellent yields (87-98%) without chromatography.
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