Diastereoselective Dihydroxylation and Regioselective Deoxygenation of Dihydropyranones: A Novel Protocol for the Stereoselective Synthesis of C1−C8 and C15−C21 Subunits of (+)-Discodermolide
The Journal of Organic Chemistry2004Vol. 69(19), pp. 6294–6304
Citations Over TimeTop 17% of 2004 papers
Abstract
Diastereoselective dihydroxylation of dihydropyranones and subsequent regioselective alpha-deoxygenation provides 1,3-trans-beta-hydroxy-delta-lactones stereoselectively. This protocol has been applied for the synthesis of C(1)-C(8) and C(15)-C(21) subunits of (+)-discodermolide.
Related Papers
- → Reductive Deoxygenation of Alcohols: Catalytic Methods Beyond Barton–McCombie Deoxygenation(2013)118 cited
- → 1,2-Deoxygenation of vic-Dihydroxyindenoimidazoles: Optimization of a Novel Deoxygenation Reagent(2004)11 cited
- → Decomposition of glucose with in situ deoxygenation in a low H2 pressure environment – Part I: Monometallic catalysts(2018)7 cited
- → 1,2‐Deoxygenation of vic‐Dihydroxyindenoimidazoles: Optimization of a Novel Deoxygenation Reagent.(2005)2 cited
- → Deoxygenation of Alcohols and CC Coupling Reactions(1998)