Palladium-Catalyzed Arylation and Heteroarylation of Azolopyrimidines
The Journal of Organic Chemistry2006Vol. 71(3), pp. 1254–1257
Citations Over TimeTop 17% of 2006 papers
Javier Mendiola, Isabel Castellote, Julio Álvarez‐Buílla, Javier Fernández-Gadea, Antonio Bermejo Gómez, Juan J. Vaquero
Abstract
A comparative study of the palladium-catalyzed arylation and heteroarylation of 5-bromoazolopyrimidines shows that aryl and electron-rich heteroaryl boronic acids gave higher yields than those obtained using the corresponding aryl and heteroaryl tributyl stannanes. In contrast, the reaction with electron-poor heteroaryl tributyl stannanes gave better results than the corresponding boronic acids.
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