Facile Synthesis of Mono-, Di-, and Trisubstituted Alpha-Unbranched Hydrazines
The Journal of Organic Chemistry2006Vol. 71(9), pp. 3627–3629
Citations Over TimeTop 24% of 2006 papers
Abstract
Methods for the alkylation of di-tert-butyl hydrazine-1,2-dicarboxylate were investigated. It was found that under mild conditions mono- or di-substituted hydrazine derivatives were obtained in good to excellent yield. Furthermore, it was shown that one of the two Boc-groups of the disubstituted derivatives was selectively removed by heating, leading to precursors for trisubstituted hydrazines.
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