Preparation of Functionalized Aryl- and Heteroarylpyridazines by Nickel-Catalyzed Electrochemical Cross-Coupling Reactions
The Journal of Organic Chemistry2007Vol. 72(15), pp. 5631–5636
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Stéphane Sengmany, Éric Léonel, Frantz Polissaint, Jean‐Yves Nédélec, Muriel Pipelier, Christine Thobie‐Gautier, Didier Dubreuil
Abstract
A general efficient electrochemical method for the preparation of aryl- and heteroarylpyridazines in a nickel-catalyzed cross-coupling reaction of 3-chloro-6-methoxypyridazine and 3-chloro-6-methylpyridazine with a range of functionalized aryl or heteroaryl halides is reported.
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