Radical (Phenylsulfonyl)difluoromethylation with Iododifluoromethyl Phenyl Sulfone
The Journal of Organic Chemistry2007Vol. 72(15), pp. 5824–5827
Citations Over TimeTop 10% of 2007 papers
Abstract
An unprecedented radical (phenylsulfonyl)difluoromethylation of terminal alkenes with PhSO2CF2I has been achieved by using Et3B/air as an initiator. This synthetic methodology was also used in the one-pot regioselective preparation of PhSO2CF2-substituted alkanes, and in the regio- and stereoselective preparation of PhSO2CF2-substituted alkenes with high E/Z ratio (up to > or =100:1).
Related Papers
- → Regioselective Chlorothiolation of Alkenes with Sulfonyl Chlorides(2019)15 cited
- → Influence of H‐Donor and Temperature on the Stereoselectivity of Radical Reactions(1987)40 cited
- → Synthesis of vinylic and cyclic sulfones via a radical addition-elimination sequence(1990)38 cited
- → Stereoselective C-C Bond Formation in Carbohydrates by Radical Cyclization Reactions; VI. Influence of the Conformation of Anomeric Radicals on the Stereoselectivity of Their Cyclization(1990)19 cited
- → γ-Oxygenated-α,β-unsaturated sulfones in radical cyclizations and cascade processes(1998)19 cited