Formal Synthesis of Cortistatins
The Journal of Organic Chemistry2011Vol. 76(8), pp. 2479–2487
Citations Over TimeTop 15% of 2011 papers
Abstract
A unified strategy toward the asymmetric facile construction of the [6.7.6.5]oxapentacyclic skeleton of cortistatins is reported, featuring intramolecular Diels-Alder (IMDA), oxidative dearomatization, and an oxy-Michael addition reaction.
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